In this podcast from his series looking at some of what's new and notable in iOS 15, Thomas Domville Shows us how you can now configure a number of accessibility settings on a per-app basis.
This feature allows you to enable or disable certain accessibility settings for a specific app or set of apps, including the Home screen. All you need to do is choose an app, toggle on the accessibility settings you want, and you'll then get options like larger text, reduced transparency, and smart invert in only the places you want them.