I was recently contacted by a customer who aimed to use my Mac app, Black Ink, to print crosswords for their relative who has low vision. At the time they contacted me the app didn't quite fit the use case, but I've since updated the app to feature new "size priorities" for both the puzzle clues and the puzzle grid. You can read more about the whole update here if you're interested:
https://redsweater.com/blog/4169/black-ink-2-4-for-mac-quick-look-printing-and-pretty-text
Using Black Ink 2.4, if you or somebody you know would benefit from solving crosswords on paper with much larger grid and/or clues, I hope it will help you/them.